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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '858344146a82fa153e68da9afa1e3f9c78e5b36c3d0d4e881c6e902e1f3c9f2a' 
  AND token = 'SYQShQ+xEm/PG3Ie99MPi68kojDBQed3ohRO5Dy6Tho=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}