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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18c0579c78254c29417129ea874b0cc164abaac609ffbf3461bb001674cf32fc' 
  AND token = '0Sd7DtRNEzJQ5bZUoXufQ98+oImIK2xJtb+yRkaEdDs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}