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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c44a69e36843cfe518c916c90520e08fd01593dfc07fd7784c6ffbd4a000f50f' 
  AND token = 'uFukfjbWiHzlscShBXriqhk4ydZVAoqke77FHHnkBHo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}