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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8aed317a5d6103f360fc5f04ed37b4b52e0c2426a33213ae35e1ab3414451727' 
  AND token = 'YUf+9NehpngQDIhKiSmwhpv25LiPcb1l5NzzWcidUBI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}