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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '596148142b1981949ddaa8337dad2fc7c3066131a574245606b13bcfa9d5a9fd' 
  AND token = 'CesgXHspPz/mTT7G8MguWCaueudPubAfxnV6i41iXgo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}