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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7c511336fe236c942b0128d32a10305ae2c69ecb023292b8287b565d748c563' 
  AND token = 'rGGK6hvLn9vHA3P212cfeh7b/MGNCkuCNBoh+nFok6g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}