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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2737cf17e0e2abb3ab06eab4eca37dbe9ae6b8a5018e7e1de98579678053b13f' 
  AND token = 'dUyntqPFsRw2Eiu0g/oLUZOQ8peb7QVKol+Psh+PDa4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}