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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '805b1989b1f2186f381f31d7122819dfb731820f6a261618f09f9c06f0114a33' 
  AND token = '/m0M2v+3QamZmpaNZUEYDKtqnpsvzbue76yKBsPEu8c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}