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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35d8b65cf3c044b03bfb6af75c2270b72cc3c0a09a4c936aa8b204330e4a3910' 
  AND token = '80+0PuZi85Ds4VigvrPT6f3MC2jeLT0KKQlj3cB7CiQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}