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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4755a9e4aea1d570ba4d02f07b2aebf45b450c67115a65ef4e684538c95777c0' 
  AND token = '7eaNUv2CRhVxBj8XJgkQLfvi/3XFhWi8J+8/5wS7LsI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}