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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8cc3ad035f5627d3f632a24ee6d318ae13b646cc3a20a811261fae9edbfbae54' 
  AND token = 'DD9s8+FAAUgiMDB/M7OLQahmNDADL8WxEa9ejxpkKrc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}