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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6689ae620c5491039f12be8012052869a42ef89c5dec33c1d6e6bcfe7fc5f50' 
  AND token = 'DEquenw8MdfhT40vVretixarimsXZqczcXCkC7oyVW8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}