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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab1c54a7d90f92408acb27c123333eac717a636c09d0454b38f39af759fd43e1' 
  AND token = 'VkGFoQy6GVYQMlwROIGNaneaQ0h4BB6Xx1YE2m/z5Jk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}