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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e1f5b560d0337a2a461fd4337d50727258689aff662f7912c8dbcbbfff21806' 
  AND token = 'wi8+e6E/EQmelAqM5jvx8yT6LP4GuT4u+PBBHAFf9fY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}