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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ed279fa93a44ba097fc73cdf8f9d14728ff47cd15c911343af10aa820619e87' 
  AND token = '3jXTQmO9yfcbJYMFrSP7VnnFI3shOnngYDLoEcyOdZs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}