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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54bb2516b565eb3bd8057490549e6659989b400f1d0fb0adf23bdfa06cb639b9' 
  AND token = 'NuO7Gf8a7hwFlh1QgvYsVw7+jtxLBCbe4grYFiEPoII=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}