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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e16b67db1f678820569d09774dfd0b066c7947624572e3c624ffe025a263a71f' 
  AND token = '+wMcJycGPAhw87uLaKS1bkTKdAgwpurVm23Kl78/O8o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}