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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cea32d72aa467d4f722edd0b867de376b6f5f627d3a7e8bdad0ddea410da896d' 
  AND token = 'kJFj7VETGGp+UDMf0GoZT7ipA/0zokdO0rtj4bNk/zM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}