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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e13fdd5f2552e1c869448c4ccc38f8e818d1e29b1bb7aa1765531d39b07ac3fd' 
  AND token = 'lVjcm35ckhuyL5Wc0+JP5cRyjT+gQT9kXGWPj3Vl/Lo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}