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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eae6fe382552caa44be597d0f420ffb9c17688a491414bad0331246a88d35dbf' 
  AND token = 'DITrqiyynoOH3UJGbIKHt+jSaw6AqOx9cbvSe3Qn9vA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}