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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f3425ffa1c484813463e3d7c816d7dfc8a8c841d8a7070d63a5b4cc6b8e5a08' 
  AND token = '+LiFafG7OC3l4ztvHSBprhfZhQp6x4QnieWrOrHXAoQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}