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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8fe2e112abb498f0a3c6293b15f9b44c8f8bd56841290d60a2cf30873ab33141' 
  AND token = 'N+FdFc4yKzZkWDkLaupYe5Kgdnow8XXbp6FXAy3sc9U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}