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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8cd8e232397ca53510851b642b8916dfb647f3d19180497d4aa43409e595346a' 
  AND token = 'CSo3pT2SBAW0d8ZnKRRtwsZdEK+a8cDttG0BQXnafWM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}