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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6fc1b5423e0270cfee71b94802a840174e09b7693ac97c609095da8dc5a4c8d6' 
  AND token = 'r5t9DGc8dWVh3aneoLLI5C+NUXZSNleI2PufLLIz3to=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}