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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64ed8fba9b42354fd3157693c368a84e9ae35993d2adac9aeb1384217c90d98e' 
  AND token = 'lXN3+ooVG6Adsnr4EwFhk59D1lyLipEmBikpD3YUAPA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}