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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f9b6d29aefd3d32416e1727eb8c177cea88d4f731cff8912e5a91deabffd4d25' 
  AND token = 'IvzI1FI/ORxKjn5WgP9Ly2bcn/8e4SIXFsRlmovJVIo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}