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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '325e306a422c8928c83a86c914556dd624fc4fa3dcb03079fdcf3de485a095f7' 
  AND token = 'wIIx/MTTFwbF/3nXkQhgJP8Hocm2+GyXb4+AHHJ4RD8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}