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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '143d25b47a542687488b8f01de340fbf5b84527cd34fe1f0f307ced955215452' 
  AND token = 'wWWNbZP9vSNBn57LDw2j41RbL4amutlGF7wXs4de+ew=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}