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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b7c1590eeeb4ce875330f71989a5eaeab8b5ca8a5bb3fbeb94d56f73a9f1081' 
  AND token = 'ndpovT+uh2lS9ArAyh3NSSEdshoR9SGUv/mYq1GW2OM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}