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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b682c2d28f568e51c9dd79ed08a04706e87ac3b3802864ee9a12aa0edc8d154' 
  AND token = '85dl6vEvRfrrO1O+/275swCp6H6LzXqGYdXZq0MaPkg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}