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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'abd7a48a537cf426d0cf5fd77158964fb02b2d5e22505a2acaad34b14e8d1c11' 
  AND token = 'UtR3yTo/eRG5YKWPAW+yoWEwoxMZaPsZhx25ondebyQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}