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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd20475cf12e3b9ba5a05b25afd0456eea0392c94c8f048c72635b150f05b96df' 
  AND token = 'RI5I0WxGCUZQN/8MGwPvRcjWSAulgJMEaJhmxCdFD5U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}