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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9680c0616cdab4e9eff711ba04eef4b30db2abfd1e3a9b817f7f06c7efda4b6' 
  AND token = 'IIJwXiv5aLoiqbNaK0qIKxuRZ280jTOtOATSKdRUeNU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}