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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52c88895d67d2e5a8b8130206d8a5002da5fbbcf24981dd8f3d5a5e0bd706cc8' 
  AND token = 'XCUs+1EBpMVKOIBjrpfazMTlQt76rns5lcqBr2ihRdY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}