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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b349011cb329b12ff3adffa083dca54aab0f17ec15c2f8a78edb540da6793e3' 
  AND token = 'ymsDTeoVZ8QAdrLsYliK7OXLVxpPi8ieTzMk9zDLdLw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}