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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7b5146899ae2ebfc80c67b4413d4830dd4bb7a9346a3c454b01bd2890edc4db' 
  AND token = 'cy7/6U2prqBa8K5koysBKWYtjuYBWB1N9ZiKQzsn+0I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}