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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '87b15a133596941b34aa89723adc831fefd6e7860b66da605c2636a23110a5e4' 
  AND token = 'tG+INPGRoL4wXA4bEMAmXKWaYh0DhMEML40ui+qg8mw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}