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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ccc03fbd0529fe5ffd480856334584ef7375535268100552fa181fad60f912ab' 
  AND token = 'JO3e1fsa5ri1KutM/xR2nU1qTKEqsnezuI8SZOSMcpE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}