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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '681a9ba1f54f311b5333eab508b47aa365478414ed455e215c2f6dd928c03f2f' 
  AND token = 'efiZbs7xqJCiOgnO0ra2UkMrBcB1E42j+H9X58pf9SM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}