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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'db1e2abbfb3a00ea73241f8be2c20fdc4fb30ab2451651cd08fe0386f075fc66' 
  AND token = 'jyo3mbJ55I6f1gOKLoUl7+RMU/UB5NixqsthbXO1IrQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}