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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41075a104653dda9cdf2c943c08ce698c3cfd6480acf0b61070368a3f05e1ff3' 
  AND token = 't4UY45Y2U+UejgDzcV4rphFNAm5HFOodtNQpam8lo4c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}