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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ec16961c7cfa6e59bf7a30559e75d2b19f68113fb3ca200cf0034c85c716663' 
  AND token = 'PRX7bJIrYp99I5pJkKXUuWM0XSqDsibJejvaevHrUqQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}