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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9cd76cde51d9a24f30892e801d25534f0b4c57ff24bee6ea174d0aba186a9280' 
  AND token = 'RShQq1PQ5R1w7B9fOcGwjYTE0FFPzOgVwuDC1uANIFE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}