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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8389aa006531dbc52143ba17bb0e915c0a31d955df5d4c7166f40d5715fd74eb' 
  AND token = 'kdQ9A1S41UXy0G9Xysu/T6arq2QjYSS4KOh6mRkfXAQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}