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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7392be78dff6c4513feafb0dbc23e779dbbd1c1ea2960978c949318c338d61c6' 
  AND token = 'Lx5ncFsdusDsLNHbqph3KWtCaNNCwIkT2PTLci4VWGk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}