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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ddc41daf34302f8106e7bda1a4e43506f34ddd0a2200ac577dbf75708a2f485' 
  AND token = 'bqJ2FSxMZ4Ve6PAE6K6YBBsERwjBcyUOcQxfyXIbDtQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}