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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a97cd48ada7c2f81ac52ebe471b6879d13f0b7c3112b27bdd3b9cbc27a8efc1' 
  AND token = 'a9OFywPdbUpeMNB5c+i9ZkfyENYncLnc/0/lR4EC7v4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}