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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ad1c4238e6463bdcfc8cfa6a527e8f39f49bc03e1362a4af3ca4a72bd066108' 
  AND token = 'RQ3FlaDVTopHhWPt1v8y0IfPqVcSn37rIeu7Rbm/kqE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}