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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd02ee35a89b1d35be57e96c5eb74955aa78f6e82a9f78d5d02d29c38ce40b056' 
  AND token = '0OHe7jrOpegfa5/fqX7GUOGBl1Sc1DdFS2bsUN4PaaY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}