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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e90fa3a3bfb8f70547321f1cfb869525280e9d19ec9e97a4bd4fc509c8020c88' 
  AND token = 'Y63hwVuDgBom7+hozkKbFn8CCoAedU9UMr54Pm0CtfI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}